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Archive for the ‘cosmeceuticals’ Category

Solvent for Ferulic Acid: non-denatured Ethanol or denatured alcohol?

Tuesday, November 17th, 2009

ethanolI recently read a post on another forum, and was slightly annoyed that an email I wrote about one of my recipes was either not understood or quoted out of context, or maybe I was not clear enough in my answer.

So, let me explain.

Ferulic acid is soluble in an alcohol.

I know that some people claim they have dissolved it in water of glycerin, but I wonder if they confuse ‘well dispersed’ with ‘dissolved’. There is a big difference, but because Ferulic acid is such a very fine powder it may be hard to physically tell the difference.

Now, what alcohols are suitable for dissolving Ferulic acid?

In my recipe I suggest ethanol or Propylene Glycol. My recipe does not suggest denatured alcohol, and I also do not suggest that people buy this.

There is a difference between ethanol and denatured alcohol.

“Ethanol, is also called ethyl alcohol, pure alcohol, grain alcohol, or drinking alcohol.” http://en.wikipedia.org/wiki/Ethanol

“Denatured alcohol is ethanol that has additives to make it toxic, unpalatable, or otherwise undrinkable. In some cases it is also dyed.” http://en.wikipedia.org/wiki/Denatured_alcohol

My recipe clearly states to use ethanol. One customer wrote that she bought ethanol, and got a bottle of denatured alcohol. This is an issue between her and the supplier she used. I suggested that she contact her supplier to verify what it was she actually ordered and received.

It may be possible to buy NON-denatured  ethanol where you live. However, in some countries this product is not available. In the USA people could buy Everclear (if available in your state), or you can simply use a high alcohol content VODKA.

Regarding the use of alcohols in skin care products.

I am well aware that a particular ‘scientific’ supplier makes a big deal out of this.

On their product pages she clearly states the solubility of her powder IF it is water or oil soluble.

If it is not, then there is no solubility info displayed, but they then claim that “The powder will not dissolve immediately, but will release components slowly into the cream/lotion.”

I think that this is a ridiculous claim to make, but it most definitely does help sell all their powders.

What really cracks me up is when I look at the ingredient listings for some of their ready-to-use products. Here we can see that they do actually use alcohol related compounds, mainly Butylene Glycol ( http://en.wikipedia.org/wiki/Butylene_glycol ).

For example, in the infamous ‘Canvas base cream’, it is the 4th ingredient in the listing (although they claim it is used for ’slip’).

So, rant over.everclear

In short, if you want to use actives that are alcohol soluble then use NON-denatured  ethanol, Everclear, or vodka. DO not use denatured alcohol.

If you don’t want to use any alcohol in your skin care products, then do not buy powders that only dissolve in alcohol.

If you want to try alternative solvents, like glycerin, please make sure that the powder has actually dissolved, not just well-dispersed.

Purity of our actives

Friday, September 4th, 2009

I sometimes get emails asking me about the purity of our products.  This is usually because of names like ‘Green Tea extract (standardized for 90% EGCG)’ or ‘Resveratrol 98%.’

There appears to be some confusion with these percentages and it appears that some people believe that our products use ‘fillers’ and are therefore no good.

Let me explain this

If someone emails me and asks “Are your products pure?” then the answer is “YES.”

They are pure, because we do not add any fillers.  So, that means when you buy our Grapeseed extract, it is 100% Grapeseed extract, NOT 60% Grapeseed extract and 40% red colored flour.

What about those percentages?

The percentages indicate the amount of the active ingredient in the powder.  For example, the active ingredient we want in Grapeseed extract are the Proanthocyanidins.

So, when you see the name Grapeseed extract 95% Proanthocyanidins, then you know that the active is 100% pure Grapeseed extract and that it has been standardized for 95% Proanthocyanidins.

The term used to show you this is the assay (http://en.wikipedia.org/wiki/Assay), we list the assay for all our products on each product’s page.

Why do we sell products that are standardized for 70% or 95%, why not 100%

Well, the more a plant extract is standardized, the more expensive the manufacturing process.  This REALLY makes a big difference.  For example, White Willow Bark extract is standardized for 25.23% Salicin, it costs hundreds of dollars per KG. It is also possible to buy the same product standardized for 95% Salicin, but that will cost THOUSAND of dollars per KG.

So, sometimes it is prohibitively expensive to buy plant extracts that are standardized at a high percentage.

We therefore buy products that are standardized at as high a percentage as possible, while at the same time keeping the price reasonable.

I really do not think you would be willing to spend US$80 for a gram of White Willow Bark 95%, especially when it is easier, a lot cheaper, and just as effective to use Salicylic acid (BHA).

Arlasolve™ DMI for enhanced delivery of active ingredients

Tuesday, September 1st, 2009

Active ingredients for skin care formulations are only as effective as the delivery system. The more efficient the delivery system, the more likely it is that the active ingredient will perform as intended. Consider all of the benefits made possible by Arlasolve DMI delivery enhancer, a safe carrier ingredient proven to place active ingredients where they are needed most on skin. A water-white liquid with excellent solvent properties, Arlasolve DMI offers formulators the option to boost the penetration of actives in the epidermis layer of skin, enabling targeted delivery for products such as self-tanners, anti-acne treatments and more.

Consumers of skin care products will notice the difference in products formulated with a delivery enhancement agent. Test results show that Arlasolve DMI contributes to fast color development of sunless tanner, with less streaking and longer lasting tan as compared with self-tanner products without the carrier ingredient. In other specialty products, such as eye-zone treatments, skin serums, scalp treatments, Arlasolve DMI may be used to enhance skin penetration. The unique solvency properties of Arlasolve DMI boosts performance of formulations such as make-up removers.

The skin care formulators’ performance booster

Ask consumers why they use a skin care product and chances are good they will purchase one they perceive to be effective. Formulators can improve the odds that an active ingredient will work to the benefit of the consumer in products designed for skin treatment. With Arlasolve DMI, the formulator can enhance the delivery of active ingredients without having to add more active. Effective delivery of actives such as salicylic acid, Vitamin C, lactic acid, hydrocortisone and hyaluronic acid can even reduce the active ingredient concentration requirement, serving to reduce the formulation cost of finished products.

Other benefits of Arlasolve DMI include:

  • Enhanced penetration of actives to the epidermis, enabling targeted delivery
  • A lower level of skin irritation with a reduction in the required concentration level of aggressive actives
  • Improved formulation shelf stability, including those susceptible to hydrolysis and transesterfication
  • Miscibility with most organic solvents and non-ionic surfactants
  • Incorporation within many product forms, including clear gels
  • A long history of safe usage
  • Ability to transport water soluble actives into skin, without recrystallization of the active
  • Ability to produce formulations with standard equipment, without the need for flammable materials handling

Arlasolve DMI / Dimethyl Isosorbide

Preservatives in skin care

Thursday, March 19th, 2009

Preservatives are chemicals that kill bacteria, fungi and molds. They are commonly present in ANY product that contains water. For this reason, oil-based skin care products and anhydrous (water free) skin care products, do not need preservatives.

However, creams, lotions and any other product where water is present, require adding a preservative.

If you do NOT use a preservative, or if you decide to believe the hype and try out a ‘natural’ preservative (such as grapefruit seed extracts), then you are putting yourself, and your skin, at RISK.

The only way you can avoid using preservatives is if you make your products FRESH every week, and store them in the refrigerator. This is what we, at BulkActives, do.

We have now started carrying three preservative systems. None are formaldehyde releasing, but they do contain other chemicals that have been getting a bad name (phenoxyethanol and the paraben family).

Let me repeat, if you make your products FRESH every week, and store them in the refrigerator, then, and ONLY then, can you avoid using preservatives.

How is L-ascorbic acid made?

Monday, March 9th, 2009

200px-l-ascorbic-acid-3d-ballsI sometimes get asked how L-ascorbic acid, also know as Vitamin C, ( CAS# 50-81-7) is made and, more often, what the source material is in the manufacturing and production of  l-ascorbic acid.

Here is the process, as I understand it.

First,  cornstarch is used to make Glucose.

Then, using a multi-step method called ‘The Reichstein process‘ , L-ascorbic acid is produced.

Short and sweet, L-ascorbic acid is made from corn.